![NG-[A_BA[COMP_TABL_ALLC]:TABLETS_160x600](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sQLdhvEmnQUJrGr-3JWASz-ozeaywVQ4Ftle-jNgUXmNF1q6tyKU06jBUsZ__ZZPei564ZIXa3Bb7JNECUtUsmQjMw4alGSatryWcFN61VbCi5IIK-Qvgfqgbj5VSa7d3fnnE5EphafKxuoT8gOKMTck09hiJT0xyGXhx-KI79UUVhS9H1mw=s0-d)
Oozing from the nipple (a discharge) that may be blood stained
Swelling of the breast
A sore (ulcer) in the skin of the breast
A nipple that is pulled into the breast (called nipple retraction)
Lumps under the arm
If you have any of these symptoms it is important to go to your GP straight away. Finding a cancer early gives the best chance of successful treatment.
Diagnosing male breast cancer
The tests for breast cancer in men usually include a painless scan using sound waves, called an ultrasound. Or you may have a breast X-ray (mammogram).
If your scan shows up an area that could be cancer, your specialist will take a sample (biopsy) of breast tissue for examination under a microscope. If these tests show that you have breast cancer, you will probably have other tests to make sure the cancer has not spread. These tests are covered on the page about further tests for breast cancer.
There are different types of breast cancer. The most common type in both women and men is invasive ductal carcinoma. The early, precancerous condition called ductal carcinoma in situ (DCIS) is diagnosed in men quite rarely. DCIS means that there are cancer cells in the breast. But the cells are all still contained inside the ducts of the breast and cannot spread. Inflammatory breast cancer and Paget’s disease and other types of breast cancer are also found very rarely in men.
Treatment for male breast cancer
The same treatments are used for breast cancer in men as for women. These are all covered in detail in the section about treating breast cancer. Treatment is decided by the stage of your cancer and whether the cancer cells have receptors for particular hormones or biological therapies. The stage means the size of the cancer and whether it has spread when it is diagnosed. The staging system is the same for men’s breast cancer as for female breast cancer.
To treat your cancer, you may have one or more of the following treatments
Surgery
Radiotherapy
Chemotherapy
Hormone therapy
Biological therapy
Surgery
The most common operation for men with breast cancer is removal of the whole breast (mastectomy) including the nipple. There is not very much breast tissue in men, so it isn’t usually possible to leave any behind. Sometimes the surgeon also removes part of the underlying muscle if it is close to the cancer.
For men diagnosed with invasive breast cancer the surgeon may remove some of the lymph nodes from the armpit. They send the nodes to the laboratory to see if they contain cancer cells. Or the surgeon may check the lymph nodes closest to the breast using a procedure called sentinel node biopsy.
For men, implants currently available don’t recreate the correct shape of a man’s breast so it is not usual to have breast reconstruction. But sometimes your surgeon may be able to improve the appearance of the chest with more surgery after mastectomy.
Creating a new nipple
Once treatment has finished you could have a new nipple created. You need to wait a few months after the mastectomy to allow any swelling to go down and the wound to heal. You can look at the pages about nipple reconstruction. Although the shape can be created, the new nipple won’t respond to touch or temperature. Other options include tattooing a new nipple and areola on to the chest. Or you can use stick on nipples – your breast care nurse can tell you where to get them.
Radiotherapy
In men, the breast cancer is always close to the muscle of the chest wall because there is so little breast tissue. So your specialist is likely to suggest radiotherapy after surgery. This treatment lowers the risk of the cancer cells growing back in the chest wall in the future. You usually have radiotherapy for a few minutes each day from Monday to Friday, for 3 to 6 weeks. Some hospitals give radiotherapy on alternate days, rather than every day.
Chemotherapy
Doctors sometimes use chemotherapy to shrink a large cancer before surgery but this is not common. Chemotherapy is most often given after surgery and before radiotherapy. Your doctor will take various factors into account to see whether you need chemotherapy to help reduce the chance of the cancer coming back.
Your doctor will usually recommend chemotherapy if you have one or more of the following
You had cancer cells in the lymph nodes under the arm
The tumour is larger than 2 cm
You are young
The cancer is high grade
Hormone therapy
Breast cancer cells can have oestrogen receptors or progesterone receptors. Most male breast cancer cells do have hormone receptors. This is known as being hormone receptor positive. About 9 out of 10 male breast cancers (90%) are oestrogen receptor positive, which means that they need oestrogen in order to grow.
Your specialist will arrange tests on your cancer cells when you are first diagnosed. This shows if the cancer cells have hormone receptors. Men have small amounts of oestrogen in their body. Hormone therapies block oestrogen from making cancer cells grow. So they can reduce the chance of the cancer coming back.
The most common hormone therapy for male breast cancer is tamoxifen. The side effects are much the same as in women. Tamoxifen can make you feel sick when you first start taking it, but this usually wears off quite quickly. The most common side effect for men and women is hot flushes. Tamoxifen may also cause weight gain, difficulty sleeping, sadness and depression.
In men, tamoxifen may cause a loss of sex drive. This has been reported in up to 3 out of 10 men taking it. There is information about how to cope with the effects of cancer treatment on your sex life in the section about coping with cancer.
Other hormone therapies are used to treat breast cancer, including aromatase inhibitors. Large studies have shown that aromatase inhibitors reduce the chance of breast cancer coming back in women who have had their menopause. But we need more research before we know how well aromatase inhibitors work in men.
Risks and causes of male breast cancer
As with women, the single biggest risk factor for male breast cancer is getting older. Most cases are diagnosed in men between the ages of 60 and 70. Other risk factors are
High oestrogen levels
Exposure to radiation
Family history or an inherited faulty gene
Klinefelter’s syndrome
High oestrogen levels
All men produce some oestrogen. This is perfectly normal. But high oestrogen levels have been linked to breast cancer. High oestrogen levels can occur in
Men who are very overweight (obese) – oestrogen is partly made in the fat (adipose) tissues of the body
Chronic liver conditions, such as cirrhosis
Some genetic conditions
Exposure to radiation
Men who have been exposed to radiation repeatedly, over a long period of time, are more likely to develop male breast cancer. This is particularly true if they were young when the radiation exposure took place.
A family history or a recognised breast cancer gene in the family
Men who have female relatives with breast cancer have an increased risk of breast cancer, especially if the women are close relatives (mother or sisters). The risk also increases if the women were diagnosed at a young age (below 40). Men, as well as women, can inherit faulty genes that can cause breast cancer.
Around 3 in 100 breast cancers diagnosed in women (3%) are thought to be due directly to an inherited faulty gene. In men, this may be more common. We think that between 10 and 20 out of every 100 diagnosed in men (10 to 20%) are due to inherited faulty genes. In men with breast cancer the BRCA2 faulty gene is more common than BRCA1.
Klinefelter’s syndrome
Klinefelter’s syndrome is a rare genetic condition where a man is born with an extra female chromosome. So he is XXY instead of XY. Men with Klinefelter’s are about 20 times more likely to get breast cancer than the average man. This makes their breast cancer risk the same as for the average woman.
Source: http://www.cancerresearchuk.org/
0 comments:
Post a Comment